The TNFAIP3 locus is implicated as a postively associated factor in rheumatoid arthritis (RA). The rs5029937 (T) and the rs6920220 (A) SNPs increase risk of RA by 20 to 40% respectively. A third SNP, rs10499194 (T) is found less often in rheumatoid arthritis but this negative association may not be statistically meaningful.
Adapted from the Wikipedia article TNFAIP3, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki
TNFAIP3 – Association with rheumatoid arthritis
The TNFAIP3 locus is implicated as a postively associated factor in rheumatoid arthritis (RA). The rs5029937 (T) and the rs6920220 (A) SNPs increase risk of RA by 20 to 40% respectively. A third SNP, rs10499194 (T) is found less often in rheumatoid arthritis but this negative association may not.
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