Many individual studies investigate possible effects of the polymorphism on, say, a personality trait or a disorder.
These may or may not find a significant association, that will need to be replicated in further studies before any major conclussion is attempted.
Examples of individual studies are:
A genetic study has found higher extraversion personality score among borderline personality disorder patients for the C-allele.
Another study found a slight association with novelty seeking among Italian mood disorder patients,
whereas a German study noted association with the trait "reward dependence".
A Chinese study found no association with suicidal behavior.
Furthermore, individual studies indicate that the SNP may be associated with rheumatoid arthritis
and not likely with the fibromyalgia syndrome.
One study implicated the C-allele in visual and auditory hallucinations in late-onset Alzheimer's disease.
Adapted from the Wikipedia article Rs6313, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki
Rs6313 – Individual studies
Many individual studies investigate possible effects of the polymorphism on, say, a personality trait or a disorder. These may or may not find a significant association, that will need to be replicated in further studies before any major conclussion is attempted.
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