The following signs may present in PBC:
*Fatigue
*Pruritus (itchy skin)
*Jaundice (yellowing of the eyes and skin), due to increased bilirubin in the blood.
*Xanthoma (local collections of cholesterol in the skin, especially around the eyes (Xanthelasma))
* Complications of cirrhosis and portal hypertension:
** Fluid retention in the abdomen (ascites)
** Hypersplenism
** Esophageal varices
** Hepatic encephalopathy, up to coma, in extreme cases.
* Association with an extrahepatic autoimmune disorder such as Rheumatoid arthritis or Sjögren's syndrome (up to 80% incidence).
Adapted from the Wikipedia article Primary biliary cirrhosis, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki
Primary biliary cirrhosis – Signs and symptoms
The following signs may present in PBC: *Fatigue. *Pruritus (itchy skin) *Jaundice (yellowing of the eyes and skin), due to increased bilirubin in the blood. *Xanthoma (local collections of cholesterol in the skin, especially around the eyes (Xanthelasma)) * Complications of cirrhosis and.
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