Necrolytic migratory erythema – Associated conditions

William Becker first described an association between NME and glucagonoma in 1942 and since then, NME has been described in as many as 70% of individuals with a glucagonoma. NME is considered part of the glucagonoma syndrome, which is associated with hyperglucagonemia, diabetes mellitus, and.

William Becker first described an association between NME and glucagonoma in 1942 and since then, NME has been described in as many as 70% of individuals with a glucagonoma. NME is considered part of the glucagonoma syndrome, which is associated with hyperglucagonemia, diabetes mellitus, and hypoaminoacidemia.

When NME is identified in the absence of a glucagonoma, it may be considered "pseudoglucagonoma syndrome". Less common than NME with glucagonoma, pseudoglucagonoma syndrome may occur in a number of systemic disorders:

*Celiac disease

*Ulcerative colitis

*Crohn's disease

*Hepatic cirrhosis

*Hepatocellular carcinoma

*Lung cancer, including small cell lung cancer

*Tumors that secrete insulin- or insulin-like growth factor 2

*Duodenal cancer


Adapted from the Wikipedia article Necrolytic migratory erythema, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki








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