Monoclonal antibody therapy – Introduction

Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells. This may then stimulate the patient's immune system to attack those cells. It is possible to create a mAb specific to almost any extracellular/ cell surface target, and thus there is a.

Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells. This may then stimulate the patient's immune system to attack those cells. It is possible to create a mAb specific to almost any extracellular/ cell surface target, and thus there is a large amount of research and development currently being undergone to create monoclonals for numerous serious diseases (such as rheumatoid arthritis, multiple sclerosis and different types of cancers). There are a number of ways that mAbs can be used for therapy. For example: mAb therapy can be used to destroy malignant tumor cells and prevent tumor growth by blocking specific cell receptors. Variations also exist within this treatment, e.g. radioimmunotherapy, where a radioactive dose localizes on target cell line, delivering lethal chemical doses to the target.


Adapted from the Wikipedia article Monoclonal antibody therapy, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki








Related Articles

Inflammatory bowel diseaseOther biological therapy agents and monoclonal antibodies have not showed as much efficacy in the treatment of IBD. These include etanercept (which is...
Monoclonal antibody technologyDr. Lorne Tyrrell pioneered lamivudine as the standard treatment for hepatitis B virus (HBV). Now a success, he observed the drug's shortcomings. Now ...
Monoclonal antibody technologyMany reports have revealed that growth of the Biotechnology sector has gained magnificent momentum with a phenomenal growth in health care sector. Bio...
Monoclonal antibody productionThrombotic thrombocytopenic purpura (TTP) is a blood disorder that causes blood clots to form in blood vessels around the body. TTP can lead to low pl...
Monoclonal antibodies therapyAids-related lymphoma is a severe disease which affects different parts of the body and requires a special treatment in order to improve the body syst...