DQ4 is associated with:
*juvenile diabetic retinopathy
The DR8-DQ4 haplotype is associated with
*papillary thyroid carcinomas
*juvenile idiopathic arthritis via DR8 allele ,
*chronic chlamydia infection,
*possibly pemphigus
DR4-DQ4(DRB1*0405:DQB1*0401) is associated with:
*autoimmune pancreatitis ,
*juvenile type 1 diabetes ,
*rheumatoid arthritis in Japanese.
The DQA1*0303:DQB1*04 haplotype is associated with:
*Crohn's disease in Japanese.
Other diseases mentioned are high altitude pulmonary edema, Vogt-Koyanagi-Harada syndrome (DRB1*0405, see above table for Japanese), HIV resistance in the US, and haemophilia A(anti-FVIII inhibitor response).
Adapted from the Wikipedia article HLA-DQ4, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki
HLA-DQ4 – DQ4 and Disease
DQ4 is associated with: *juvenile diabetic retinopathy. The DR8-DQ4 haplotype is associated with. *papillary thyroid carcinomas. *juvenile idiopathic arthritis via DR8 allele , *chronic chlamydia infection, *possibly pemphigus.
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