Anergy may be taken advantage of for therapeutic uses. The immune response to grafting of transplanted organs and tissues could be minimized without weakening the entire immune system— a side effect of immunosuppressive drugs like cyclosporine. Anergy may also be used to induce activated lymphocytes to become unresponsive with autoimmune diseases like diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Likewise, preventing anergy in response to a tumoral growth may help in anti-tumor responses.
Adapted from the Wikipedia article Clonal anergy, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki
Clonal anergy – Clinical significance
Anergy may be taken advantage of for therapeutic uses. The immune response to grafting of transplanted organs and tissues could be minimized without weakening the entire immune system— a side effect of immunosuppressive drugs like cyclosporine.
If you enjoyed this article, please consider sharing it!
Related Articles
NF-κB is widely used by eukaryotic cells as a regulator of genes that control cell proliferation and cell survival. As such, many different type...
Mutations in the ferroportin gene are known to cause an autosomal dominant form of iron overload known as Type IV Haemochromatosis or Ferroportin Dise...
Interleukin-8 is often associated with inflammation. As an example, it has been cited as a proinflammatory mediator in gingivitis and psoriasis.[http:...
”K. pneumoniae” can cause the disease Klebsiella pneumonia. Research conducted at King’s College, London has implicated molecular mi...Related Articles
NF-κB is widely used by eukaryotic cells as a regulator of genes that control cell proliferation and cell survival. As such, many different type...
The genus Acremonium currently contains approximately 100 species, of which most are saprophytic, being isolated from dead plant material and soil. Ma...Mutations in the ferroportin gene are known to cause an autosomal dominant form of iron overload known as Type IV Haemochromatosis or Ferroportin Dise...
Aminopeptidases play a role in the metabolism of several peptides that may be involved in blood pressure and the pathogenesis of essential hypertensio...Related Videos
Rheumatoid arthritis is an inflammatory disease that can affect many joints in your body. Learn more about the causes, symptoms and some treatment options for...
Ellen Shmueli, living with rheumatoid arthritis for more than 10 years, shares her experience of being diagnosed and finding a rheumatologist who worked with her...
A rheumatologist describes the effects of rheumatoid arthritis, a chronic inflammatory disease of the joints, its most common symptoms and the treatment options available....