Common adverse drug reactions (ADRs) associated with clindamycin therapy — found in over 1% of patients — include: diarrhea, pseudomembranous colitis, nausea, vomiting, abdominal pain or cramps, rash, and/or itch. High doses (both intravenous and oral) may cause a metallic taste, and topical application may cause contact dermatitis. Diarrhea, vomiting, and nausea are common if the individual lies down for an extended period of time within 30 minutes of taking Clindamycin. In addition, severe heart burn can be expected for up to 3 days if the individual does not stay in an elevated position for at least 30 minutes.
Pseudomembranous colitis is a potentially-lethal condition commonly associated with clindamycin, but which occurs with other antibiotics as well. Overgrowth of ''Clostridium difficile'', which is inherently resistant to clindamycin, results in the production of a toxin that causes a range of adverse effects, from diarrhea to colitis and toxic megacolon.
Rarely — in less than 0.1% of patients — clindamycin therapy has been associated with anaphylaxis, blood dyscrasias, polyarthritis, jaundice, raised liver enzyme levels, and/or hepatotoxicity.
Adapted from the Wikipedia article Clindamycin, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki
Clindamycin – Adverse effects
Common adverse drug reactions (ADRs) associated with clindamycin therapy — found in over 1% of patients — include: diarrhea, pseudomembranous colitis, nausea, vomiting, abdominal pain or cramps, rash, and/or itch.
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