Biological response modifiers – Introduction

Biological response modifers, also known as BRM's, are substances that the human body produces naturally, as well as something that scientists can create in a lab. These substances arouse the body's response to an infection.

Biological response modifers, also known as BRM's, are substances that the human body produces naturally, as well as something that scientists can create in a lab. These substances arouse the body's response to an infection. Some of these are used to treat arthritis, cancer, and some other diseases. Biologics include Monoclonal antibodies, Interleukin-2, Interferon, various types of colony-stimulating factors (CSF, GM-CSF, G-CSF)

"Immunotherapy makes use of BRMs to ''enhance'' the activity of the immune system to increase the body's natural defense mechanisms against cancer" whereas BRMs for rheumatoid arthritis aim to reduce inflammation.

Some of the effects of BRMs include nausea and vomiting, diarrhea, loss of appetite, fever and chills, muscle aches, weakness, skin rash, an increased tendency to bleed, or swelling.


Adapted from the Wikipedia article Biological response modifiers, under the G. N. U. Free Documentation License. Please also see http://en.wikipedia.org/wiki








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